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Home ❯ Research projects ❯ INVESTIGO GEVAB 100045ID18

Funds Source:

Government of Catalonia

Period:

15/11/2022 to 15/11/2024

Project typology:

Individual project

Project status:

ACTIVE

Funding Entity:

AGAUR

Funding:

66,216 €

Propietats de la barrera hematoencefàlica

El projecte postdoctoral, finançat amb Programa Investigo, estudiarà les propietats de la barrera hematoencefàlica (BBB) ​​que consisteix en una estreta xarxa de capil·lars sanguinis al cervell que separen el sistema circulatori del sistema nerviós central.

Les seves propietats particulars es basen en la interacció dinàmica entre les cèl·lules endotelials cerebrals i altres cèl·lules circumdants, especialment els astròcits. El becari postdoctoral dissenyarà i sintetitzarà una bastida tridimensional que recapitula les principals característiques de la matriu extracel·lular BBB i serveixi de plataforma per co-cultivar cèl·lules endotelials microvasculars del cervell humà i astròcits corticals humans.

Research groups

GEVAB – Vascular Engineering and Applied Biomedicine Group

The GEVAB group develops its activity in two main areas: the development of biomaterials to treat vascular pathologies and the study of other clinical needs, integrating knowledge from medicine, biology, chemistry, physics, mathematics and computing.