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Home ❯ Research projects ❯ TumorOut (Innovative mRNA vaccine against lung cancer)

TumorOut (Innovative mRNA vaccine against lung cancer)

Funds Source:

Government of Spain

Period:

01/01/2023 to 31/12/2025

Project status:

ACTIVE

Funding:

250,000 €

Innovative platform of targeted polymeric nanoparticles for efficient personalized therapy against lung cancer

This is a TRANSCAN3 (ERA-NET Cofund) project that the involves the coordinated activities of 6 european research centres coordinated by IQS  to develop a novel therapy to treat lung cancer (https://transcan.eu/output-results/funded-projects/tumorout.kl)

 

This project involves the coordinated activities of 6 european research centres coordinated by IQS to develop a novel therapy to treat lung cancer. Non-small cell lung cancer (NSCLC) treatment shows unprecedented improvement with immune checkpoint inhibitors (ICIs) but only a minority of NSCLC patients (25%) demonstrate long-term benefit. Our preliminary data and working hypothesis is that therapeutic mRNA vaccination, coupled with co-targeting of antigen-presenting cell (APC) immunosuppressive in a patient stratification strategy will sharply increase the number of patients who will benefit from ICIs.

Research groups

GEMAT – Materials Engineering

The GEMAT group (Materials Engineering Group) conducts its activity in three main areas: the development of new functional materials, surface engineering and biomaterials.