
The NanoTher group conducts research in nanomedicine Engineering for Targeted Interaction with Physiological Barriers.
Research lines:
Polymeric Nanoparticles
Development of proprietary polymer-based nanocarriers for the precise and controlled delivery of small molecules, biologics, and genetic materials. Our custom-designed polymers enable responsive, programmable delivery profiles tailored to specific therapeutic needs.
Extracellular Vesicle-Based Drug Delivery
Bioengineering and cargo loading of extracellular vesicles (EVs) to harness their natural targeting properties. We repurpose EVs as next-generation nanocarriers for controlled and biocompatible drug delivery in challenging biological environments.
Overcoming Biological Barriers
Design and formulation of nano- and microscale delivery systems capable of selectively interacting with mucosal surfaces, epithelial tissues, and immune-resident cells. Focus on enabling non-invasive administration routes, such as pulmonary and nasal delivery, and enhancing blood–brain barrier permeability.
mRNA Vaccines and Therapeutics
Design and formulation of mRNA-based vaccines for both prophylactic and therapeutic applications in human and veterinary medicine. Emphasis on optimizing delivery vectors to enhance translation efficiency and immunogenicity.
Combination Cancer Immunotherapies
Development of multifunctional nanocarriers capable of co-delivering therapeutic nucleic acids (e.g., mRNA, miRNA, siRNA) and immunomodulators. These platforms aim to synergize immune activation and tumor targeting, paving the way for next-generation combination immunotherapies.
Other Applications of Nano- and Microencapsulation
Exploration of encapsulation technologies for broader applications beyond biomedicine. These include the delivery of active ingredients in cosmetics, dermopharmaceuticals, nutraceuticals, and detergency, where controlled release, protection of actives, and enhanced performance are critical.
Members

Cristina Fornaguera Puigvert, PhD
Department of Bioengineering

Laura Angulo García
Department of Analytical and Applied Chemistry

Pau Castells Colldeforns
Department of Bioengineering

Alexander Fabian Biewald
Department of Bioengineering

Jennifer Fernández Alarcón, PhD
Department of Bioengineering

Maria Gil Vives
Department of Bioengineering

Patricia González Sáenz, PhD
Department of Bioengineering

Marta Guerra Rebollo, PhD
Department of Bioengineering

Jordi Guixeras Carreras
Department of Bioengineering

Elena Haro Martínez
Department of Bioengineering

Mar Losada Baranera
Department of Analytical and Applied Chemistry

Natalia Rodríguez Murillo
Department of Analytical and Applied Chemistry

María José Sánchez Gómez
Department of Bioengineering

Vladimir Stamenkovic, PhD
Department of Bioengineering