Infraestructura y equipos de bioproceso para la realización de proyectos de desarrollo, optimización, escalado y fabricación de lotes de prueba. Indicada para cultivos de microorganismos (bacterias, levaduras y hongos) en batch y fed-batch en condiciones aerobias y anaerobias. Organismos clase 1 (no patógenos). Incluye operaciones de downstream para las primeras etapas de asilamiento de bioproductos.
Equipment and technologies
It features a surface area of 130 m2 including:
- Bioprocessing space, which houses the 144 L bioreactor, auxiliary services and process equipment (DSP) including cell disruption, centrifugation, microfiltration, ultrafiltration and lyophilisation.
- Reagents and Product storage, with a 4ºC cold chamber and a -20C chest for the storage of samples, culture media and production batches that require cold preservation.
- Auxiliary Laboratory, for the preparation of inoculums, culture media and analytical techniques. Equipped with a laminar flow cabinet, fume hood, incubators, baths, centrifuges, spectrophotometer, analyser, and a 10 L bioreactor for inoculum preparation and for preliminary viability and optimisation studies.
144L Biorecator: Bioreactor for cultures, with a net volume going from 20 to 100 L. (Bionet, model F3-100)
Equipment and technologies
- 144 L Bioreactor (Bionet)
- 10 L Bioreactor (Bionet)
- Tangential microfiltration and ultrafiltration system (Bionet)
- Cell disruptor (Gea Niro Soavi)
- Process centrifuge (Alfa Laval)
- Freeze dryer with chamber (Coolvacuum)
