ADHERE (Evaluation of bioresorbable endovascular patch for treatment of aortic dissection)
Investigador principal
Grupo de investigación
Fuente de financiación:
Otras entidades
Periodo:
11/03/2024 a 10/03/2027
Tipología del proyecto:
Proyecto consorciado
Estado del proyecto:
ACTIVO
Entidad financiadora:
La Marató de TV3
Financiación:
159.912,50€
First human trial with endovascular bioresorbable patch for aortic dissection
This is a collaborative project betwen IQS and Hospital Clinic de Barcelona funded by Fundació La Marato TV3.
Aortic dissection is a dramatic disease with unacceptable mortality rates (30-80%). Current treatments present severe limitations and must be replaces. IQS and Hospital Clínic have joined forces to solve this unmet need by developing the ultimate solution for aortic dissection: an endovascular device that allows for endogenous regeneration of the aorta instead of artificial replacements. Our biomimetic patch is released on the aorta using a minimally invasive deployment system. The patch mimics the natural mechanical properties of the aorta to secure smooth integration in the native tissue.The main objectives of the project are:
- To execute the regulatory bench testing experiments that allow for first in human authorization.
- To define the operation limits for the device, with especial focus on patient aortic geometry.
- To get regulatory authorization to start a first in human study.
- To perform the first in human clinical study of the device in ten type B aortic dissection patients.